Freeman Technology will be presenting a poster ‘The
characterisation of granulation wet masses using powder rheometry', at the
International Granulation Conference in Lausanne, Switzerland from 20-22 June
2011. The poster describes how to steer wet granulation towards a desirable
endpoint using Freeman Technology's FT4 Powder Rheometer. Reliable endpoint
detection is crucial for the efficient and consistent production of granules of
optimal quality. To download a copy of the poster, visit www.freemantech.co.uk.
Widely used in the pharmaceutical and chemical industries,
wet granulation converts powders into granules to, for example, improve flow
and reduce segregation. Its successful application requires recognition
of the point at which the granules attain the properties
needed to form a product of the desired quality. The FT4 Powder Rheometer
measures the Basic Flow Energy (BFE) of a granulation, a powder property
that is independent of scale. Research shows that changes in BFE
precisely indicate the transition point from wet mass to granules, which
usually marks the endpoint of a granulation process, making the parameter
useful in development, optimization and scale-up studies.
Freeman Technology's FT4 Powder Rheometer is a universal
powder tester that uses patented dynamic methodology, fully automated shear
cells and several bulk property tests, including density, compressibility and
permeability to quantify powder properties in terms of flow and processability.
Correlating this data with processing performance enables users to optimise
powder processes.