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SMART Freeze Dryer Technology Optimizes Cycle Development

publication date: May 27, 2010
 | 
author/source: Primetek Solutions
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spscientificpr7-image.jpgFTS SMART Freeze DryerTM technology from SP Scientific, is a unique control software tool proven to enable development scientists to accelerate and streamline the arduous task of developing and optimizing freeze drying cycles. 

Based upon unique control algorithms developed by some of the world's leading lyophilisation experts - SMART Freeze Dryer technology is available exclusively for the SP Scientific LyoStarTM and Process Development freeze dryer ranges. 

SMART Freeze Dryer Technology enhances freeze dry cycle development in several important ways.  Traditional cycle development relies on the experience and intuition of the development scientist, along with a trial and error approach. This often requires weeks of development time, and multiple test cycles can consume scarce and valuable active ingredients. SMART technology enables the developer to generate the right cycle on the first attempt.  Due to the trial-and-error approach used in conventional freeze-dry cycle development, it is common practice for scientists to build-in "safety factors" in their cycles to ensure product integrity.  By adding this safety margin, it is estimated that most production lyophilisation cycles are excessively long, often by several days. SMART Freeze Dryer technology allows the development scientist to create a streamlined but safe cycle that can shave days off the production cycle. This efficiency gain can eliminate production bottlenecks, expand capacity and reduce production costs.

Data analysis on traditional freeze-drying cycles requires careful sampling and hours of detailed calculations by an experienced freeze-drying scientist.  SMART technology features a unique feedback loop that provides detailed data on the pharmaceutical product and the freeze-drying process, including product resistance, heat flow and product thickness. Ready-access to such data can enhance scale-up efforts, provides a data trail for regulatory compliance, and frees-up valuable scientist time for other tasks.

For further information on SMART Freeze Dryer technology please contact SP Scientific on +1-845-255-5000 or email freezedryer@spscientific.com.  

SP Scientific is a leading manufacturer of laboratory to production scale freeze dryers / lyophilizers, centrifugal evaporators and concentrators, thermal control system and glassware washers. The company sells its products under well-known brands including Hotpack®, VirTis®, FTSTM and Genevac®. SP Scientific has ISO 9001:2000 registered production facilities in the USA and Europe. 




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