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Articles & Application Notes

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In the news

  Direct HPAE-PAD Analysis of Sialic Acids in Glycoprotein Hydrolyzates
Feb 3, 2012
Thermo Fisher ScientificThermo Fisher Scientific is pleased to announce a new method that allows sialic acids in five representative glycoproteins to be determined by acid hydrolysis release and high-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD). Application Update 180: Direct Determination of Sialic Acids in Glycoprotein Hydrolyzates by HPAE-PAD demonstrates that determination of N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) on a Thermo Scientific Dionex CarboPac PA20 Fast Sialic Acid column is specific and direct...
  Thermo Fisher Scientific Collaborates with US EPA to Improve Holding Time and MDLs for Chromate in Drinking Water
Jan 30, 2012
Thermo Fisher ScientificThermo Fisher Scientific Inc. is pleased to announce that its participation in the secondary validation of US EPA Method 218.7 for hexavalent chromium, Cr(VI), in processed drinking water is complete. Cr(VI) is a toxic compound regulated by the EPA for certain wastewaters. Our scientists have been participating in a collaborative project with the EPA Office of Ground Water and Drinking Water in Cincinnati to improve the holding time and sensitivity of US EPA Method 218.6...
  Simple, Rugged, and Accurate New Method for the Assay of Risedronate in Drugs
Jan 25, 2012
Thermo Fisher ScientificThermo Fisher Scientific Inc. is pleased to announce a new method that exceeds the U.S. Pharmacopeia (USP) monograph specifications for risedronate sodium analysis. This method is based on an anion-exchange separation with a 4 × 250 mm Thermo Scientific Dionex IonPac AS7 (USP L48) column using edetate disodium (EDTA) eluent to resolve risedronate from related compounds. Application Note 289: Evaluation of the USP Risedronate Sodium Assay demonstrates the linearity, detection limits...
  Unlocking the potential of Stem Cells in Neuroscience Research
Jan 25, 2012
Stem Cells in Neuroscience ResearchAMSBIO has written an informative technical article to enable neuroscience researchers to learn more about a new method to control and direct differentiation of physiologically relevant neural cell types using stem cell qualified reagents. Stem cells have revolutionized our approaches to and understanding of neuroscience. The key to research success is the ability to control and direct differentiation into physiologically relevant neural cell types...
  Bruker publish article ‘Compound Based Scanning: Making the Transition From SQ to TQ GC-MS Easier’
Jan 18, 2012
SCION TQPublished in "Chromatography Techniques", December 2011, and authored by experts from Bruker's Chemical and Applied Markets division (Fremont, California) a new article examines how Gas Chromatography (GC), coupled to a triple quadrupole Mass Spectrometer (GC-MS/MS-QqQ) operated in MRM mode, is rapidly becoming the preferred technique for multi-residue analysis in complex matrix samples by analytical laboratories...
  Sports Drug Testing Lab Accelerates Sample Preparation
Jan 17, 2012
miVac Duo sample concentratorGenevac has announced an applications report that details how its miVac Duo sample concentrator has been used by a leading testing laboratory to develop a new sample preparation method to help curb sports doping. Recent developments in applying mass spectrometry to proteomics means that it is becoming feasible for doping laboratories to routinely detect and confirm the abuse of peptide hormones by sportsmen and women. Using mass spectrometry to detect and confirm the abuse of peptide hormones is preferred to the use of immunoassay techniques as the methodology is able to...
  Thermo Fisher Scientific Couples Chromatography and Mass Spec Systems to Develop Method for Detecting Arsenic in Apple Juice
Jan 12, 2012
IC-ICP-MSThermo Fisher Scientific Inc., the world leader in serving science, today announced that its Dionex ICS-5000 reagent-free ion chromatography system can be coupled with the Thermo Scientific XSERIES 2 ICP-Q-MS to create a proven IC-ICP-MS method for detecting trace elements, including levels of organic and inorganic arsenic in apple juice. A Consumer Reports investigation recently revealed elevated levels of arsenic in juice samples...
  Thermo Fisher Scientific Launches Technical Library of LC-MS Solutions for Quick and Easy Analysis of PPCPs and Pesticides in Water
Dec 14, 2011
Thermo technical library of LC-MS solutions for water analysisThermo Fisher Scientific Inc., the world leader in serving science, today announced the availability of a new technical library of LC-MS solutions for water analysis, including application information on the detection of pharmaceuticals and personal care products (PPCPs) and pesticides. 
  Thermo Fisher Scientific Announces New Method for Low Level Detection of Volatile Nitrosamines in Tobacco
Dec 6, 2011
Thermo Scientific TSQ Quantum XLS triple quadrupole GC-MS/MS system Thermo Fisher Scientific Inc., the world leader in serving science, today announced a new comprehensive method that uses triple quadrupole GC-MS/MS to achieve lower levels of detection of volatile nitrosamines (VNA) in tobacco. The new method allows environmental laboratories, tobacco companies and government agencies to efficiently separate VNAs while lowering detection limits...
  Simplified and Reproducible Separation of Ethyl Sulfate Impurity in Indinavir Sulfate
Dec 6, 2011
Thermo Fisher ScientificThermo Fisher Scientific Inc. is pleased to announce a new method that uses ion chromatography (IC) to separate ethyl sulfate in an indinavir sulfate drug sample. Indinavir sulfate is a specific and potent inhibitor of HIV-1 protease and is widely used in the treatment of AIDS. Application Note 284: Determination of Ethyl Sulfate Impurity in Indinavir Sulfate Drug Using Ion Chromatography demonstrates that only the addition of deionized water to the IC system is required to deliver reproducible chromatography while avoiding the time, labor, and potential error of manual eluent preparation...
 
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