All articles from AMS Biotechnology (Europe) Ltd

Extensive Range of Bromodomain Protein Domains & Profiling Kits
Mar 15, 2012

• AMSBIO provides an extensive portfolio of bromodomains and kits suitable for bromodomain profiling, inhibitor screening assays, and drug discovery. Bromodomains (BRDs) are 110 amino acid long domains that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine...

Article describes potential of Stem Cells in Neuroscience Research
Feb 9, 2012

• AMSBIO has written an informative technical article to enable neuroscience researchers to learn more about a new method to control and direct differentiation of physiologically relevant neural cell types using stem cell qualified reagents. Stem cells have revolutionized our approaches to and understanding of neuroscience. The key to research success is the ability to control and direct differentiation into physiologically relevant neural cell types...

ELISA kits enable precise analysis of key neurodegenerative-related biomarkers
Jan 26, 2012

• AMSBIO has expanded its range of rat specific ELISA kits that enable precise analysis of key neurodegenerative-related biomarkers while minimizing the use of precious samples. Visitors to the recent Neuroscience 2011 meeting in Washington DC responded enthusiastically to AMSBIO's range of over 2300 rat specific ELISA kits tailored for the sensitive and specific quantification of your cytokine, growth factor, or chemokine of interest. Particular interest was shown in new rat specific analyte ELISA kits for various Neurotrophins, TGFb1 and rat leptin as well as a series of ganglioside ELISAs...

Unlocking the potential of Stem Cells in Neuroscience Research
Jan 24, 2012

• AMSBIO has written an informative technical article to enable neuroscience researchers to learn more about a new method to control and direct differentiation of physiologically relevant neural cell types using stem cell qualified reagents. Stem cells have revolutionized our approaches to and understanding of neuroscience. The key to research success is the ability to control and direct differentiation into physiologically relevant neural cell types...

Stem cell qualified mouse Leukemia Inhibitory Factor (mLIF)
Nov 29, 2011

• AMSBIO has added mouse Leukemia Inhibitory Factor (mLIF) to its extensive range of stem cell research products. Functionally tested with mouse ES cells, the affordably-priced AMSBIO recombinant mLIF combines both high quality and high activity. Mouse Leukemia Inhibitory Factor is a lymphoid factor involved in a number of biological processes including neural and hematopoietic cell differentiation, bone and fat metabolism, and mitogenesis of certain factor dependent cell lines...

Videos Demonstrate Utility of Unique 3D Cell Culture Technology
Oct 12, 2011

• AMSBIO have added a major new suite of video presentations and a bibliography of downloadable technical papers that demonstrate the utility of alvetex® - a unique synthetic scaffold that enables routine 3D cell culture. alvetex® is a highly porous polystyrene scaffold engineered into a 200µm thick membrane which provides a 3D space into which cells can invade, proliferate and grow. The vertical axis of the third dimension enables additional layers of cells to form complex 3D interactions...

Optimised Gene Delivery Solution for Hard-to-Transfect Cells
Oct 5, 2011

• AMSBIO has introduced GeneInTM - a new transfection reagent specifically designed to transfect stem cells and primary cells. Comparative studies against other commercially available reagents show GeneInTM to be superior in transfection efficiency with minimum cytotoxicity...

Chemically Defined Stem Cell Cryopreservation Solution
Sep 28, 2011

• STEM-CELLBANKER® from AMSBIO is a chemically defined freezing medium with optimized formulation for stem cells and iPS cells storage as well as other valuable cells. Supplied ready-to-use with a simple usage protocol, STEM-CELLBANKER® is completely free of serum and animal derived components, and contains only European or US Pharmacopoeia graded ingredients...

AMSBIO and Chondrex Cooperate On Arthritis & Inflammation Research
Sep 21, 2011

• AMSBIO has announced a pan European partnership with Chondrex Inc. to market their high quality arthritis and inflammation reagents to academics and pharmaceutical companies that do research in these fields. The range includes a suite of high quality reagents such as highly purified cartilage collagen and collagen monoclonal antibodies to provide scientists with the necessary tools to study the pathogenesis as well as to develop and screen potential therapeutics for Rheumatoid Arthritis (RA)...

Investigating protein-binding properties of Heparin, Heparan Sulfate and other glycosaminoglycans (GAGS)
Sep 12, 2011

• AMSBIO has announced a suite of exciting new products for investigating the protein-binding properties of Heparin, Heparan Sulfate (HS) and other glycosaminoglycans (GAGS). Such investigations have traditionally been constrained by the need for chemical modification prior to attachment to inert or derivatized surfaces. The AMSBIO Heparin/GAG Binding Plate offers a simple solution to this problem - the specially-prepared plate surface adsorbs GAGS without modification whilst maintaining their protein-binding characteristics...

AMSBIO moves to support the Glycobiology research community
Aug 23, 2011

• AMSBIO has announced a package of initiatives to support the Glycobiology research community following the recent announcement by Seikagaku Corporation that they plan to discontinue their research reagents and glycobiology biochemicals business as of September 30th 2011...

Potent Reagent for Reliable Stem Cell Differentiation
Jul 14, 2011

• AMSBIO announces ec23®* - a stable synthetic retinoid that has been proven in independent testing** to potently induce and reliably control stem cell differentiation. Stem cells self renew and have the ability to differentiate into a variety of cell types. They represent a valuable renewable resource from which functional tissues can be derived. Such materials can subsequently be used for research, disease modeling, drug testing and ultimately therapeutic applications...

Reproducible and Quantifiable Directed In Vivo Angiogenesis Assessment Assays
Jul 11, 2011

• AMSBIO has announced a new range of Directed in vivo Angiogenesis Assay (DIVAATM) kits that address the short-comings of the traditional plug assay by controlling the site for angiogenesis, increasing reproducibility, conserving test compounds, and supplying more statistical data for quantitative analysis. This range of kits is designed to test for activation, inhibition and tube formation...

Pluripotent Stem Cell Line Assessment qPCR Kit
Jun 29, 2011

• AMSBIO has announced the launch of the PluriPCRTM Kit, a new benchmark to revolutionize the definition of stem cell pluripotency. The PluriPCR kit has been designed as a quantitative, easy to use, and reliable assay of five genes strongly specific to pluripotency. These genes: Oct-3/4, Nanog, DNMT3b, Dppa4, and Rex1 are expressed by human embryonic stem cells (hESC) and induced pluripotent stem cells (iPSC); all are sharply down-regulated during differentiation.

Reproducible undifferentiated growth of pluripotent stem cells
Jun 20, 2011

• AMSBIO is a leading supplier of Mouse Embryonic Fibroblasts (MEFs) and Newborn Human Foreskin Fibroblasts (NuFFs) for mouse and human pluripotent stem cell culture (ES and iPS cells). All AMSBIO feeder cell products are meticulously derived and comprehensively tested on mouse and human ES stem cells to ensure robust and consistent performance with every lot...

Genuine 3D Cell Culture Technology
Jun 10, 2011

• AMSBIO has announced the launch of Alvetex® - a unique cell culture scaffold that, for the first time, enables genuine 3D cell culture to be grown routinely and cost-effectively. Already successfully applied to numerous applications including drug toxicity models with liver cells, skin raft assays and bone remodeling studies - Alvetex® provides a stable and inert scaffold for cells to grow, mimicking in vivo growth and formation of tissues in the body...

AMSBIO Announces US Office
May 16, 2011

• AMSBIO has announced, as of 31st March 2011, the opening of a new North American subsidiary company - AMSBIO LLC. After successfully selling innovative life science technologies, biotools and services directly to North American researchers, the new office will be a fully integrated entity supporting the AMSBIO product line with a dedicated sales and service facility in Orange County, California...

A Robust, Quantitative Alternative to the Scratch Assay
Mar 11, 2011

• New independent research demonstrates that the OrisTM Cell Migration Assay presents a superior quantitative, high throughput alternative to the scratch assay. Cell migration is integral to many physiological processes, including embryonic development, tissue regeneration, and wound healing. One assay commonly used to study cell migration is the scratch assay creating a cell-free gap, or "scratch", on a confluent cell monolayer...

Knockdown Cell Lines for DNA Repair Studies
Mar 2, 2011

• AMSBIO has announced a new range of highly efficient knockdown cell lines covering the Base Excision DNA Repair pathway. The new range of 20 DNA Repair Knockdown cell lines was developed to enable scientists to study the molecular etiology of tumour genomic instability and to exploit it in oncology research. The AMSBIO DNA Repair Knockdown cell lines are based upon target-specific LN428 glioblastoma shRNA lentivirus transduced cells that are rigorously qualified and mycoplasma free.

Animal-free Preparation of Human Serum Albumin
Jan 25, 2011

• AMSBIO has announced the launch of ecoHSA - an animal-free preparation of the human albumin gene produced in the seeds of Asian Rice (Oryza sativa). Commercial human albumin proteins extracted from plasma have multiple and invaluable uses in cell culture work.

Highly Efficient, Reproducible Non-Cytotoxic Transfection Reagent
Jan 14, 2011

• GenePORTER® Gold from AMSBIO is a new highly efficient and reproducible lipid-based reagent for effective transfection of a wide variety of cell lines. Molecular target delivery faces many barriers, from crossing the cell type-specific extracellular membrane, to cytoplasmic degradation and translocation across the nuclear membrane. To be effective, the transfection reagent/DNA complexes must overcome all of these challenges whilst minimizing cytotoxicity

Extensive Range of Purified Full Length Human Proteins
Jan 4, 2011

• AMSBIO is now able to offer a range of over 4,000 full length affinity purified human proteins expressed in HEK293 cells and derived using an extensive collection of human cDNA clones. The new range is currently the broadest offering of human proteins produced in human cells. It has been prepared to ensure optimal preservation of protein structure, post-translational modifications and functions.

Ideal controls for PCR, RNA microarray & antibody array studies
Dec 21, 2010

• The AMSBIO range of Universal Reference Products (RNA, cDNA and Protein Lysate) has been expanded to include standards for studies involving humans as well as for animal species including Monkey, Dog, Mouse, Rat, and Chicken. These products provide ideal controls for high throughput PCR, RNA microarray and antibody array studies

Kits for Accurate and Reproducible mRNA Amplification
Dec 9, 2010

• ExpressArt® mRNA Amplification Kits from AMSBIO offer an elegant technological solution for qRT-PCR and gene expression array studies that overcomes the limitations of sample quality and quantity. ExpressArt® technology allows reproducible and precise analysis of challenging samples including Formalin-Fixed Paraffin-Embedded (FFPE), laser captured micro-dissections, needle biopsies, and circulating tumor cells.

Kits for improved nucleic acid recovery from FFPE samples
Nov 23, 2010

• AMSBIO has announced new kits for the isolation of high quality RNA from Formalin-Fixed Paraffin-Embedded (FFPE) tissues and LCM samples that can be applied both to qRT-PCR and a variety of microarray platforms.

Selection Guide for Apoptosis Assay Kits & Reagents
Oct 26, 2010

• AMSBIO has announced an expanded range of assay kits and reagents for the detection and analysis of apoptosis. A new selection guide has been created by AMSBIO to provide researchers with a quick and easy way to identify and select the best tools to measure apoptosis.

New Cell Migration Assay Dramatically Reduces Cost Of High Content Screening
Oct 18, 2010

• AMSBIO has announced the launch of the first of a new generation of cell migration assays designed specifically for fully automated high throughput screening (HTS) utilizing high content screening (HCS) and high content imaging (HCI) systems.

High purity reagents for glycobiology and glycoanalysis
Oct 1, 2010

• 

  Specialist in high purity reagents for glycobiology and glycoanalysis - AMSBIO - has announced a number of new and unique kits for proteoglycan research.

Optimised E.coli Strain Expresses Insoluble Proteins In Soluble Form
Sep 30, 2010

• AMSBIO has announced Solu BL21TM Competent E. coli, a significantly improved BL21 host strain for soluble mammalian protein expression. Using a directed evolution approach, a mutant strain of BL21(DE3) E. coli has been developed that can produce soluble protein in the majority of cases where expression in the parent BL21(DE3) yielded no detectable soluble product.

Standardized Comet Assay System Ensures Reproducible Results
Aug 31, 2010

• The CometAssay® Electrophoresis System and new CometAssay® Neutral Control cells from AMSBIO enable investigators to consistently optimize neutral Comet assays for highly reproducible results, and to standardize neutral electrophoresis methods between individual users and laboratories.

Ready-to-Use Gene Delivery Tools
Aug 25, 2010

• AMSBIO has announced a new range of expression ready lentiviral particles that allow easy gene delivery into hard to transfect cells including primary cells, non-dividing cells and cells in suspension.

AMSBIO-New Magnetic Beads Enable Faster Protocols
Aug 10, 2010

• AMSBIO has announced a new range of MagSi magnetic beads that incorporate a novel ferro fluid to combine the advantages of small beads and large surface with the magnetic performance and strength of larger beads.

New Magnetic Beads Enable Faster Protocols
Jul 21, 2010

• AMSBIO has announced a new range of MagSi magnetic beads that incorporate a novel ferro fluid to combine the advantages of small beads and large surface with the magnetic performance and strength of larger beads.

Protein Standards for Mass Spectrometry Analysis
Jul 20, 2010

• AMSBIO has announced a new service whereby it can generate high quality Mass Spectrometry (MS) standards for over 5,000 human proteins. Produced in human HEK293T cells and labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, the full length proteins with appropriate post-translational modifications are the best choice for accurate identification and quantification of protein biomarkers

Homogeneous Assay Kits Minimize Assay Complexity
Jun 30, 2010

• AMSBIO has released 4 new homogeneous 384-well format AlphaScreen assay kits - JMJD2A, JMJD2B, JMJD2C, PRMT5 and G9a (a histone methyltransferase).

New Kits for Assessing Oxidative Stress
Jun 24, 2010

• AMSBIO has announced an expanded range of assay kits for the detection and quantification of oxidative stress biomarkers and antioxidants.

Tools to Study Genomic Instability
Jun 8, 2010

• AMSBIO has announced a new second generation PARP in vivo Pharmacodynamic Assay that accurately measures net poly (ADP-ribose) (PAR) levels in cellular extracts and has been used to document differences in PAR levels in human tumour lysates from a variety of tissues, organs and xenografts.

Comprehensive Biorepository of Genomic & Proteomic Tissue Products
May 25, 2010

• AMSBIO offers a comprehensive range of certified tissue products for genomic and proteomic research including genomic DNA, cDNA, RNA and protein.

Highly Reproducible Gene Delivery for Stem Cell Research
May 10, 2010

• AMSBIO have announced a range of ready-to-use lentivirus supernatant products suitable for many kinds of gene delivery applications including stem cell research.

Non-Animal Recombinant Proteins for Cell Culture & Tissue Engineering Applications
May 4, 2010

• AMSBIO has announced a new range of recombinant proteins that can substitute extracellular matrix proteins that are currently extracted from mouse sarcoma.

Easy and Economic Generation of Functional siRNAs
Apr 22, 2010

• The Turbo Dicer siRNA Generation Kit from AMSBIO enables easy and cost-effective generation of a large number of small interfering RNAs (siRNAs) from full-length target genes.

Highly Reproducible Gene Delivery
Apr 8, 2010

• AMSBIO have announced a range of ready-to-use lentivirus supernatant products suitable for many kinds of gene delivery applications including mammalian protein expression, stable cell line construction, cell signal pathway localization and stem cell research.

Sensitive & Specific anti-DDK Antibody for FLAG Epitope Tagging
Mar 18, 2010

• AMSBIO has announced 4C5 - an anti-DDK monoclonal antibody for the detection of DYKDDDDK epitope - the same protein sequence as FLAG-tag*.

Assay Kits for Measuring the Complete Range of HDAC Enzymes
Feb 15, 2010

• AMSBIO has announced 2 new histone deacetylase (HDAC) cell-based assay kits that provide an easy tool for studying the activity and inhibition of the full range of HDAC enzymes (1-11).

Rabbit Monoclonal Antibodies for Immunohistochemistry
Feb 5, 2010

• AMSBIO has announced a new portfolio of rabbit monoclonal and polyclonal antibodies for Immunohistochemistry (IHC) applications. A rabbit custom antibody service is also available.

Accelerate Your Cell Migration Research
Jan 13, 2010

• AMSBIO has announced the addition of the OrisTM Pro Cell Migration Assay to its range of 96-well cell exclusion zone assays for performing cell migration and cell invasion experiments.

A Novel HAMA Blocker for Reduction of Immunoassay Interference
Dec 18, 2009

• amsbio has introduced TRU Block, a highly potent reagent that actively blocks the heterophilic antibody (HA) interference in immunoassays including but not limited to Human Anti-Mouse Antibody (HAMA) interference.
  

Homogeneous Fluorescence-based Assay for Detecting Intracellular Calcium Mobilisation
Dec 9, 2009

• Amsbio's Screen Quest™ Calcium Assay kit provides a homogeneous fluorescence-based assay for detecting intracellular calcium mobilisation across a broad spectrum of biological targets

Custom Tissue Sections & Microarrays
Dec 8, 2009

• amsbio offers services for custom acquisition, procurement and preparation of tissue sections and tissue microarrays from a wide range of animal and plant species according to client specification.
  
  Drawing upon many years of experience amsbio is able to provide expert consultancy on the design and development of custom tissue sections and tissue microarrays

Standardisation of Direct Detection of DNA Damage In Cells.
Sep 27, 2009

• Amsbio has announced a novel complete assay system for direct detection of DNA damage in cells which includes CometSlides™, reagents, control cells and an electrophoresis unit.